Tamara Abou Antoun, B.S., Ph.D.
LAU Extension: 2107
Office Location: CHSC 6101
Dr. Abou Antoun joined the Lebanese American University School of Pharmacy in October 2010. She came from the Children’s National Medical Center in Washington, DC, where she was as a post-doctoral Research Associate studying the molecular mechanisms of tumor stem cell recurrence and treatment-resistance, and the development of targeted therapy to eradicate and reduce the rate of recurrent treatment-resistant malignancies. Previously, she was a Research Technologist at the Cleveland Clinic Foundation in Cleveland, Ohio, and the National Institutes of Health in Bethesda, Maryland. Her Ph.D. studies focused on the molecular mechanisms that promote pediatric brain tumor invasion and metastasis.
Education and Training
- B.S. in Biomedical Sciences (Honors), Victoria University, Melbourne, Australia
- Ph.D. in Molecular Medicine, The George Washington University, Washington, DC
- Post-doctoral Fellow, Children’s National Medical Center Washington, DC
Honors and Awards
- Identifying and isolating cancer stem-like cells to understand their mechanism of treatment-resistance and metastatic recurrence
- Al-Dimassi S, Abou-Antoun T, El-Sibai-M. Cancer cell resistance mechanisms: a mini-review. Clin Transl Oncol2014;16:511-516.
- Chakrabarti L, Abou-Antoun T, Vukmanovic S, Sandler AD. Reversible adaptive plasticity: a mechanism for neuroblastoma cell heterogeneity and chemo-resistance. Front Oncol 2012;2:82. doi: 10.3389/fonc.2012.00082. Epub 2012 Aug 2.
- Abouantoun TJ, Castellino RC, MacDonald TJ. Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells. J Neurooncol 2011;101:215-226.
- Abouantoun TJ, MacDonald TJ. Imatinib blocks migration and invasion of medulloblastoma cells by concurrently inhibiting activation of platelet-derived growth factor receptor and transactivation of epidermal growth factor receptor. Mol Cancer Ther 2009;8:1137-1147.
- Dayer AG, Cleaver KM, Abouantoun T, Cameron HA. New GABAergic interneurons in the adult neocortex and striatum are generated from different precursors. J Cell Biol 2005;168:415-427.